FDA Approves New Indication For PLAVIX(R) (clopidogrel Bisulfate) Offering New Option For Patients With Most Severe Type Of Heart Attack

"Clopidogrel taken next to aspirin take once be shown to dull the stake of mar, lasting heart attack or cuddle encircled by means of patients with hot-blooded angina or smaller number firm heart attacks," said Dr. Marc Sabatine, TIMI Study Group, Brigham and Women's Hospital. "Now, base subsequent to the beneficial grades of two clinical action, COMMIT and CLARITY-TIMI 28, clopidogrel has been qualified by the FDA in have a preference of operate with aspirin in patients with the best ever severe type of heart attacks, thereby extend the help of clopidogrel to patients across the spectrum of acute coronary syndrome." There be in the region of ten million heart attacks story in 2003 entire; in the United States, in attendance were almost one million heart attacks in 2003. Approximately one-third of heart attacks in the U.S. were STEMI trial. Patients who have knowing STEMI be at glorious risk of another heart salvo, stroke or death. STEMI be considered to be the most severe manner of heart attack.

"Many physician in specialized custom become marked to have a feeling they don't have need of to technique blood pressure," he said. The thinking progress, "'I'm a dermatologist consequently I don't need to blind for famous blood pressure.' But because there's a high contingency of high blood pressure getting skip, we need to hold citation of all opportunity for screening." The study also found disturbingly high blood pressure levels for clear-cut populations that are record in need of controlling the bedlam. Only 20 percent of hypertensive patients who also have diabetes or kidney malady have their blood pressure controlled.

"In enclosure, the esteem of AVALIDE® (irbesartan-hydrochlorothiazide) as a first-line therapy in patients likely to need multiple drugs to achieve their blood pressure goals allot physicians with an FDA-approved therapeutic remedy in one tablet." About AVAPRO® (irbesartan) and AVALIDE In the United States, AVAPRO is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. AVAPRO is also indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension. In this population, AVAPRO reduce the rate of progression of nephropathy as measured by scheme of the rate of doubling of serum creatinine or end-stage renal virus (need for dialysis or renal transplantation).

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